TRIMETHOPRIM-SULFAMETHOXAZOLE

Description

it should only be used in cases where, in the judgment of the physician, the benefits of treatment outweigh any possible risks, while considering the use of a single antibacterial agent. Official guidance on the appropriate use of antibacterial agents and the local prevalence of resistance should be considered. As the in vitro susceptibility of bacteria to antibiotics varies geographically and over time, the local situation should always be taken into account when selecting antibiotic therapy. Bactrim® F should only be used to treat or prevent infections that are known or suspected to be caused by bacteria or other sensitive microorganisms. In the absence of such data, local epidemiology and patterns of sensitivity may contribute to the empirical selection of appropriate antibiotic therapy.

• Ear and respiratory tract infections:

Acute exacerbation of chronic bronchitis.

Otitis media in children.

Treatment and prophylaxis (primary and secondary) of Pneumocystis jirovecii pneumonia in children and adults, especially in immunocompromised hosts.
• Infections of the urogenital tract: Infections of the urinary tract and chancroid.

• Gastrointestinal tract infections: Typhoid and paratyphoid fever, shigellosis (susceptible strains of Shigella flexneri and Shigella sonnei when antibacterial therapy is indicated), traveler’s diarrhea caused by enterotoxigenic Escherichia coli, and cholera (as an adjunct to fluid and electrolyte replacement) .

• Other infections: Infections caused by a wide range of organisms (treatment possibly in combination with other antibiotics), such as brucellosis, acute and chronic osteomyelitis, nocardiosis, actinomycetoma, toxoplasmosis and South American blastomycosis.