Description
• Irritable bowel syndrome.
• Bacterial overgrowth of the small intestine.
• Adjuvant in the treatment of secondary hyperammonemia and liver failure (hepatic encephalopathy).
• Symptomatic diverticular disease of the colon.
• Pre and post-surgical prophylaxis of infectious complications in surgery of the gastroenteric region.
• Acute and chronic intestinal infections due to Gram positive or Gram negative bacteria; diarrheal syndrome.
• Diarrhea due to an alteration in the balance of the normal intestinal flora (traveler’s diarrhea, enterocolitis).
Indications:
Xifaxan 400 mg Tablets are commonly prescribed for:
- Traveler’s Diarrhea: Caused by Escherichia coli.
- Hepatic Encephalopathy Prevention: To reduce recurrence in patients with liver disease.
- Small Intestinal Bacterial Overgrowth (SIBO): As part of a treatment plan for patients diagnosed with SIBO.
- Irritable Bowel Syndrome with Diarrhea (IBS-D): Symptomatic treatment of IBS-D.
Key Features:
- Targeted Gastrointestinal Action: Designed to act locally within the digestive tract with minimal systemic absorption.
- Broad-Spectrum Efficacy: Effective against a variety of bacteria associated with gastrointestinal infections.
- Short Course Treatment: Typically prescribed for a short duration for optimal effectiveness in treating infections.
Dosage and Administration:
- Take as prescribed by your healthcare provider, typically 400 mg three times a day.
- Can be taken with or without food.
- Ensure the full course of treatment is completed to prevent the development of antibiotic resistance.
Contraindications and Precautions:
Contraindications:
- Allergy to rifaximin or other rifamycin derivatives.
- Severe liver dysfunction (use with caution or consult a doctor).
Precautions:
- Inform your doctor if you have liver conditions or a history of gastrointestinal issues.
- Avoid using if there is blood in your stool or a fever.
Side Effects:
- Common: Nausea, abdominal pain, bloating, or headache.
- Rare but Serious: Allergic reactions, liver issues, or severe gastrointestinal symptoms.
- Contact a healthcare provider immediately if any severe side effects occur.
Storage Instructions:
- Store at room temperature (15–30°C), away from sunlight and moisture.
- Keep out of reach of children.
Why Choose Xifaxan 400 mg?
Xifaxan offers a safe and effective treatment for gastrointestinal infections with a targeted action in the gut, providing relief for conditions such as traveler’s diarrhea, IBS-D, and more. It’s well-tolerated and works with minimal systemic effects.






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