AMOEBRIZ MEBENDAZOLE-QUINFAMIDE

Description

AMOEBRIZ® is indicated for the treatment of intestinal parasitosis caused by acute or chronic intestinal amebiasis, caused by Enterobius vermicularis (pinworms); Ascaris lumbricoides (earthworms); Trichuris trichiura (whipworms); Necator americanus, Ancylostoma duodenale (hookworms); Strongyloides stercolaris; Taenia solium, Taenia saginata (tapeworms) and Hymenolepis nana.

In patients living in endemic areas, regular treatment with AMOEBRIZ® (3-4 times a year) can significantly reduce reinfection with a good level of clinical significance.

Amebicide, intraluminal antiparasitic.

Product Description:
AMOEBRIZ (Mebendazole-Quinfamide 300/150 mg) Tablets are a combination medication designed to treat intestinal infections caused by both parasitic worms and Entamoeba histolytica (amoebiasis). Each dose consists of 2 tablets, providing a total of 300 mg of Mebendazole and 150 mg of Quinfamide.

• Mebendazole: An anthelmintic agent that effectively treats common intestinal worms such as roundworms, hookworms, and whipworms. It works by inhibiting the parasites’ ability to absorb glucose, leading to their death and expulsion from the body.
• Quinfamide: An antiprotozoal medication that specifically targets Entamoeba histolytica, responsible for amoebiasis, and works by disrupting the parasite’s ability to reproduce and survive in the intestines.

Indications:

• Treatment of intestinal worm infections such as roundworms (Ascaris lumbricoides), hookworms (Ancylostoma duodenale, Necator americanus), and whipworms (Trichuris trichiura).
• Treatment of amoebiasis caused by Entamoeba histolytica.

How It Works:

• Mebendazole: Prevents parasitic worms from absorbing essential nutrients, leading to their death.
• Quinfamide: Inhibits DNA synthesis in Entamoeba histolytica, effectively eliminating the infection.

Dosage and Administration:

• Recommended Dose: 2 tablets (300 mg Mebendazole and 150 mg Quinfamide) as a single dose.
• Swallow the tablets whole with water, preferably with food to minimize stomach irritation.
• Consult a healthcare provider for the appropriate dosage and treatment plan based on the individual’s health condition.

Precautions:

• Not recommended for individuals with hypersensitivity to Mebendazole, Quinfamide, or other related compounds.
• Use with caution in patients with liver or kidney conditions.
• Consult a doctor if pregnant, breastfeeding, or taking other medications.

Side Effects:

• Common: Mild stomach upset, nausea, dizziness, or headache.
• Rare: Allergic reactions such as skin rash, swelling, or difficulty breathing.

Storage Instructions:

• Store at room temperature (20°C-25°C).
• Keep away from moisture and direct sunlight.
• Keep out of reach of children.

Note: Always follow the healthcare provider’s instructions and read the package insert for additional information.