Description
POSIPEN 12H exerts its bactericidal action against most Staphylococcus and Streptococcus. It is indicated in: tonsillitis, pharyngitis, bronchitis, bronchopneumonia, pneumonia with multiple foci, even in their serious complications, such as empyemas, pyoneumothorax with or without pneumatoceles, and lung abscesses caused by Staphylococcus aureus, including penicillinase producers. It is also indicated in a wide variety of skin and soft tissue infections such as: impetigo, bullous impetigo, furunculosis, pyoderma, cellulitis, hydrosadenitis, scalded skin syndrome (Lyell syndrome and Ritter’s disease) and Staphylococcus infected wounds. Also, in septic arthritis, osteomyelitis and pyomyositis.
POSIPEN 12H can be used in buccodentomaxillary infections caused by gram-positive germs such as Staphylococcus and Streptococcus that cause gingivitis, periapical abscesses, pericoronitis, maxillomandibular osteomyelitis and periodontal infections.
Indications:
Posipen 12H XR is commonly prescribed for:
- Skin and Soft Tissue Infections: Such as cellulitis, abscesses, and impetigo.
- Bone and Joint Infections: Including osteomyelitis.
- Respiratory Tract Infections: Caused by susceptible bacteria.
- Other Staphylococcal Infections: Where beta-lactamase production is a concern.
Key Features:
- Extended-Release Formulation: Ensures sustained efficacy with twice-daily dosing.
- Penicillinase-Resistant: Effective against beta-lactamase-producing bacteria, including Staphylococcus aureus.
- High Strength: Ideal for moderate to severe bacterial infections.
Dosage and Administration:
- Typical Dosage: One tablet every 12 hours or as prescribed by a healthcare provider.
- Take on an empty stomach, at least 1 hour before or 2 hours after meals, with a full glass of water.
- Complete the full course of treatment to prevent resistance.
Contraindications and Precautions:
Contraindications:
- Allergy to dicloxacillin, other penicillins, or cephalosporins.
- History of severe allergic reactions to beta-lactam antibiotics.
Precautions:
- Inform your doctor about any history of kidney or liver disorders, gastrointestinal diseases, or allergies.
- Use with caution during pregnancy and breastfeeding under medical supervision.
Side Effects:
- Common: Nausea, diarrhea, mild abdominal discomfort, or skin rash.
- Rare but Serious: Severe allergic reactions (e.g., anaphylaxis), liver enzyme abnormalities, or blood disorders.
- If serious side effects occur, seek immediate medical attention.
Storage Instructions:
- Store at room temperature (15–30°C), away from direct sunlight and moisture.
- Keep out of reach of children.
Why Choose Posipen 12H XR Dicloxacillin 1 g?
Posipen 12H XR provides a reliable and convenient solution for managing resistant bacterial infections. Its extended-release formulation and penicillinase-resistant properties ensure effective treatment with fewer daily doses, improving patient adherence and outcomes.






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